HA PRO® ACETYLATED SODIUM HYALURONATE

Nkọwa dị mkpirikpi:

Sodium acetylated hyaluronate site grafting akụkụ nke hydroxyl otu nke sodium hyaluronate n'ime acetyl otu site kemịkalụ mmeghachi omume, ya mere o nwere ma hydrophilicity na lipophilicity, nke nwere ike na-egwu okpukpu abụọ moisturizing, antioxidant, mgbochi mkpali, ịrụzi keratin mgbochi, na imeziwanye akpụkpọ elasticity na ndị ọzọ. ọrụ ndụ na-arụ ọrụ.Ọ nwere ike ime ka akọrọ na adịghị ike nke akpụkpọ ahụ dịkwuo mma, mee ka akpụkpọ ahụ dị nro na nke na-agbanwe agbanwe, a pụkwara iji ya mee ihe n'ọtụtụ ebe na ngwaahịa ịchọ mma kwa ụbọchị.

Nkọwa ngwaahịa

Okwu Mmalite ngwaahịa

Njirimara anụ ahụ na kemịkalụ: Ọdịdị dị ọcha ma ọ bụ ntụ ntụ edo edo, na-agbaze ngwa ngwa na mmiri.

Njirimara ngwaahịa dị ka n'okpuru

1. Super moisturizing

2. Na-ekpochapụ free radicals, anti-oxidant na mgbochi ịka nká

Ndozi mgbochi mkpali

1. Super moisturizing

A na-eji ngwọta ammonium sulfate zuru ezu iji mee ka iru mmiri dị na 81%.Chọpụta ọdịiche dị arọ n'etiti HA na AcHA ntụ ntụ na-etinye maka 1h-8h, glycerin njikwa dị mma, na-akọwa njigide mmiri ya;dị ka e gosiri na Figure 1, ebe ACHA bụ nọmba 2: Nnwale na-egosi na n'ime 1h, AcHA nwere nnọọ elu karịa glycerin na The mmiri njide nke nkịtị HA;N'ime 1-8h, njide mmiri nke ihe nlele niile rere ka oge na-aga, mana njide mmiri nke ACHA ka dị elu karịa nke njikwa ndị ọzọ.

HA1: sodium hyaluronate dị ala dị ala;HA2: sodium hyaluronate acetylated;

HA3: sodium hyaluronate dị arọ nkịtị;

Ọgụgụ 1: Nkezi ọnụọgụ mmiri na-ejide ihe nlele ọ bụla n'oge ọ bụla

2. Na-ekpochapụ free radicals, anti-oxidant na mgbochi ịka nká

Na ngwọta ethanol, 1,1-diphenyl-2-trinitrophenylhydrazine (DPPH) ụmụ irighiri ihe nwere ike ịmepụta radicals n'efu nwere nitrogen.Ọ nwere nnabata siri ike na 517nm, na onye na-agbapụta radical free nwere ike ijikọ ya na otu elektrọn ya iji mebie ihe ngwọta ahụ.A na-eji ụkpụrụ a iji chọpụta n'ụzọ dị iche iche ikike antioxidant nke ihe ndị na-arụ ọrụ ndụ.Site na ule mmetụta na ọgbọ nke DPPH free radicals, e gosiri na e jiri ya tụnyere ndị na-ahụ maka njikwa, acetylated HA nwere ikike ịchụpụ DPPH free radicals, ma gafere ọkwa radical free radical molecular arọ.

HA1: sodium hyaluronate dị ala dị ala;

AcHA: acetylated sodium hyaluronate

Ọnụọgụ 2: Ọnụego mkpochapụ radical efu nke sodium acetylated hyaluronate

3.Mgbochi mgbochi mkpali

Ekpebiri ikike mgbochi mkpali site na usoro immunosorbent jikọtara enzyme.Nnyocha egosiwo na 1µg/mL lipopolysaccharide (LPS) nwere ike ime ka mkpụrụ ndụ HaCaT mepụta ihe ndị na-eme ka ọ bụrụ ihe na-adịghị mma, na ike nke ihe ndị na-emepụta ihe na-egbochi ọkwa nke ihe mkpali ELISA nwalere.Dị ka e gosiri na foto 3, ma e jiri ya tụnyere hyaluronic acid nkịtị, okwu 1L-1a dị na acetylated hyaluronic acid group na-ebelata nke ukwuu, na ule ahụ gosiri na AcHA nwere ikike dị ukwuu iji gbochie ihe ndị na-egbuke egbuke.

HA2: sodium hyaluronate acetylated;

HA3: sodium hyaluronate arọ molekul nkịtị:

Ọgụgụ 3: Nkwupụta nke 1L-1a na sel dị iche iche

Nkọwapụta ngwaahịa

Aha ngwaahịa	Acetylated sodium hyaluronate
Nkọwa ngwaahịa	White ma ọ bụ odo ntụ ntụ ma ọ bụ granule
Uru ngwaahịa	Super moisturizing, AcHA nwere nnọọ elu moisturizing Njirimara karịa glycerin na nkịtị HA; Na-ekpochapụ radicals n'efu, mgbochi oxidation na mgbochi ịka nká, AcHA nwere ikike ịbọ ọbọ DPPH free radicals, ma gafere ogo radical free radicals. Na-egbochi mbufụt na ịrụzi, AcHA nwere ikike doro anya igbochi ihe mkpali ma e jiri ya tụnyere hyaluronic acid nkịtị;
Nkọwapụta ngwaahịa	njirimara	A. Infrared absorption spectrophotometry
		Mmeghachi omume agba BA na-apụta na uronic acid
		C. Ọ na-enye mmeghachi omume (a) nke sodium
	Acetyl ọdịnaya	23.0-29.0%
	pH	5.0-7.0
	Ọnwụ na ihicha	≤10.0%
	Ihe fọdụrụ na mgbanye	11.0% -16.0%
	viscosity dị n'ime	0.50-2.80dL/g
	Igwe dị arọ (dị ka Pb)	≤20ppm
	Arsenic	≤2.0pm
	Nitrogen ọdịnaya	2.0-3.0%
	Ọnụ nje bacteria	≤100CFU/g
	Ebu & Yist	≤30CFU/g
	Staphylococcus aureus	Ihe ọjọọ/g
	Pseudomonas aeruginosa	Ihe ọjọọ/g
Ọnọdụ Nchekwa	Chekwaa n'ime ụlọ anaghị ekpuchi ikuku, nke nwere ndò.
Nkwakọ ngwaahịa	Dị ka ndị ahịa chọrọ
Ndụ nchekwa	Afọ abụọ (nkwakọ ngwaahịa anaghị emeghe)

Ntuziaka maka ojiji

Usoro ọgwụgwọ akwadoro: 0.01% -0.1%;

Ihe eji eme ihe: ngwa ngwa soluble na mmiri, nwere ike tinye ya ozugbo na mmiri mmiri;akpụkpọ ahụ na-enye ume ọhụrụ na ọ bụghị nnyapade

Ngwa ngwa: etinyere na ihe ịchọ mma dị ka ihe kacha mkpa, nkpuchi ihu, ude, ude mmiri, wdg.

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